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A slow and steady revolution is sweeping the market for erectile dysfunction drugs – Cialis. Most people may not even be aware of it. Lilly ICOS, the pharmaceutical alliance, which launched the blockbuster drug Cialis, announced that the drug has achieved 1 billion dollars in global sales since launching in Europe less than two years back. In fact Cialis has become the top Erectile Dysfunction treatment in France, since January 2005, based on the latst market data, easily overtaking Viagra, the first brand to be launched in this market. It is also doing very well in United Kingdom, Italy, Germany, United States, Canada, Australia, Mexico and Brazil. So much so that a Lilly ICOS press release contained these words from Rich Pilnik, President of Lilly's EMEA region "We are very pleased with the performance of Cialis and the steady development of the brand since its launch two years ago. Millions of men suffer from ED and the growth of the market demonstrates that patients are speaking to their healthcare providers about ED and seeking treatment options." Not only has Cialis been able to expand the market but it has also eaten heavily in the market share of Viagra from Pfizer, the first drug to be launched in this market and Levitra from Glaxo-Bayer-Schering Plough. In fact Cialis was the second PDE5 inhibitor drug to become available in Europe. It is currently promoted in approximately 100 countries including the United States, Australia, Brazil, Mexico, Canada and across Europe and Asia for Erectile Dysfunction. According to Paul Clark, Chairman and Chief Executive Officer of ICOS Corporation. "Passing the $1 billion mark is an important milestone for Lilly ICOS and a great accomplishment for the Cialis team. Since 2003, men with erectile dysfunction have had a choice of oral treatments for their condition - a condition which may impact on relationships and daily life." Beyond all the hype and the jubilation is the sheer superiority of Cialis over all the other drugs available in this indication. To understand the benefits of Cialis, we need to firstly understand this complex condition. Erectile Dysfunction or Impotence is defined as the inability to ensure and maintain an erection sufficient for sexual intercourse. ED affects an estimated 180 million men worldwide . 90 percent of ED cases are related to a physical or medical condition, such as diabetes, cardiovascular diseases, and prostate cancer treatment, while 10 percent are due to psychological causes . In many cases, however, both psychological and physical factors contribute to the condition. Where physical factor play an important role PDE-5( Phosphodiaterase) inhibitors have a significant role to play. These include drugs like Sildenafil (Viagra) and Vardenafil(Levitra). But none are as good as Tadalafil(Cialis). Why? Firstly let’s understand how PDE-5 inhibitors work. They work by inhibiting the enzyme phosphodiasterase-5 which is responsible for degrading another enzyme called cGMP(cyclic Guanosine Mono Phosphate) which through a series of reactions is responsible for the synthesis of nitric oxide. Nitric oxide is an important vasodilator responsible for dilation of the blood vessels that supply blood to the penis. Thus, there is an increase in the blood supplied to the penis and this increased blood engorges the penis and leads the formation of an erection through hydraulic pressure. All PDE-5 inhibitors work in the same way but because they are different molecules, they also have different properties. The body quickly eliminates both Sildenafil and Vardenafil. Therefore their action lasts for only 4 hours, while Tadalafil(Cialis) is absorbed and eliminated slowly therefore it remains in the body for a longer period of time. Therefore its duration of action is 9 times that of other drugs - 36 hours. This ensures that Cialis will act over a whopping 36 hours and any patient on Cialis does not need to have hurried sex , but sex at his or his partner’s leisurely pace. That is why Cialis has been nicknamed as “Le Weekend Pill” in France. It allows the man to relax with his partner and have spontaneous sex. Also other drugs like Viagra act on the enzyme PDE-6, which is found in the eyes, leading to bluish discolouration of vision, which will not occur with Cialis. Cialis can be taken with a 100% fat meal and there will be no change in it’s action. The same is not true for Sildenafil or Vardenafil, which are affected by food. All this makes Cialis currently the best drug for erectile dyfunction. What further adds to it’s appeal are programmes like “The Cialis Promise” from Lilly ICOS which guarantees free trial with a rival drug in case Cialis does not work. With this kind of confidence oozing from Lilly ICOS, there is reason to believe in the promise of Cialis. Cialis is available at any neighbour chemist on providing a doctor’s prescription or one can buy Cialis online. An online prescription is generated on filling a short form and on payment through credit card, one can be rest assured of getting Cialis discreetly. What more cheap generic Cialis is also available online. This will further reduce your medical bills. The low cost is like an icing to the Cialis cake or pudding for that matter . But, as is said, the proof of the pudding lies in the eating - So go for Cialis. top pennis enlargement pills enlarement free penis pills sample pnis enlargement picture surgical pnis enlargement penis enlagement technique penis enlagement doctor safe penis enhancement compare penis enlarement pills

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If you have ever had a cold sore, you can only hope you never get anther one. We are hoping to provide you with some useful information about what they are, how you get them and some preventative measures you can take to avoid them. Core sores are infections that can occur around or in the mouth. Also referred to herpes simplex, there are 2 strains known as type 1 and type 2. Cold sores are most often caused by type 1 or HSV-1. Type 2 or HSV-2 is most often related to genital herpes where blisters form in the genital area. Cold sores can easily be transmitted between people through saliva or some other direct contact. Blisters often form on the lips and or inside the mouth. These can frequently turn into painful ulcers that make gums turn red and swell. Some people can suffer from fever, muscle aches, swollen neck glands and irritability when they get a cold sore. They can last anywhere from 3 days to 2 weeks depending on treatment. Herpes simplex type 2 or genital herpes is transmitted sexually. The genital area becomes sore, itchy, tender and just plain painful. Visual signs are blisters on the penis or on the vagina area. These blisters soon turn into painful sores that can last up to 3 weeks. Cold sores can often appear if one is under stress, is getting a cold or other virus, is exposed to long periods of sunlight, is pregnant or after a tooth has been pulled. If you find you are prone to getting a cold sore, the best prevention is to keep your stress level down as much as possible, get lots of rest if you start feeling under the weather and make sure to use a strong SPF sunscreen lip balm when outdoors. Also, avoid kissing anyone who has one! The best prevention for herpes simplex type 2 is for you to wear a latex condom if you are the male or insist your partner wears one if you are the female. pnis enlargement stretcher guide to penis enlagement penile enlargment video cheapest penis enlargement pills sex vig rx best enhancement exercise penis surgical penile enlargment penis enlarement pump penis enlargement pic

a) Cut price holiday. b) Plastic surgery. c) Both in a package along with other discount options. Tick your choice. Is it (c)? Do you really believe on the marketing gimmicks that plastic surgeries are as easy and acceptable as going to a holiday? Can you just have it done by any person and from anywhere? Sorry, a logical brain can not subscribe to this view. However this is not the only marketing gimmick we have seen so far. Last year around 65000 operations had taken place in UK. And one can easily make out the reason why such advertisements are seen round the corner. Not only the film actors and actresses or pop stars, but general people, who can afford to have it, are also taking cosmetic surgery to boost up their confidence and self esteem. It is all about getting everything right and only a perfectionist knows, what it does mean. One may find a lot of such advertisements in the back covers of a number of Woman’s Magazines. People are advertising even for plastic or cosmetic surgeries for less in a lot of substandard hospitals away from United Kingdom. Some even do not care about GP’s reference. One cannot help supporting the views of General Medical Council that all patients should be referred by his or her general physician or some other consultant before taking a plastic surgery for their own good. In many of such cases they hardly even think about the issue regarding ‘aftercare’. Whatever let the surgery be, tummy tuck or Breast enlargement, aftercare is as much important as the operation itself had been. Many research studies have shown that where aftercare is poor, the rate and extent of complications increases. Having a weight loss surgery without an extended aftercare programme is never a safe option. The operating surgeon ideally needs to keep in touch with the general physician of the patient for a long time after the surgery for safety reasons. To add to this, one must remember that, any doctor may call himself or herself a plastic surgeon even without any specific surgical training. There are no official restrictions to it if the doctors do not feel any moral obligations to it. This is reason enough for you to be careful enough while selecting a plastic or cosmetic surgeon. However, if financial assistance is needed, there are a lot of cosmetic surgery and treatment providers who may help you in getting it easily. Never settle for gimmicks; it never pays in the long run. penis enlarement picture herbal natural penis enlargement penis elargement pills product penis enhancement surgery cost pnis enlargement procedure penis enlagement pic before and after penis girth enlargement homemade penis elargement penis enlargement pic

Growing old is not all fun. We’re proned to rheumatism, gout, vision loss, hearing loss, and worst of all sexual dysfunction. Since now, doctors used to think that most cases of erectile dysfunction were psychological in origin. According to many studies conclusions, many of them recognize that, at least in older men, physical causes may play a primary role in 60% or more of all cases. For instance, the leading cause in men over the age of 60 is atherosclerosis, or narrowing of the arteries, which can restrict the flow of blood to the penis. Impotence may also be caused by damage to the nerves of the penis, as a result of certain types of surgery or neurological conditions such as Parkinson's disease or multiple sclerosis. Men with diabetes are especially at risk for impotence because of their high risk of both atherosclerosis and a nerve disease called diabetic neuropathy. More and more experts concluded now that all male sexual dysfunction problems rise from medical conditions like prostrate cancer, diabetes, kidney diseases, lower back pain or drug abuse, smoking and excessive alcohol. Though psychological factors like stress and depression can play a vital role in causing ED, chronic sexual dysfunction follows a physical cause. Men need to understand the importance of adopting healthier lifestyles, including losing weight and giving up cigarettes. Men who have resisted advice about smoking and weight loss may react differently when they learn that cigarettes and obesity can contribute to impotency. Men who must avoid sexual activity because of their cardiac status should not use any of drugs or other treatments for ED. It is estimated that more than 322 million men will suffer from male impotence by 2025. An improvement in men’s diet and lifestyle patterns can reduce the chances of ED in men. It is also found that men who recognize erectile dysfunction problems and seek treatments are willing to make tremendous lifestyle changes to get rid of the disorder. Oral drugs such as Viagra, Cialis and Levitra are popular pills which treat ED in men. Also vacuum devices, injections and micro vascular surgeries provide patients with effective treatments. enargement manhattan penis penis enlargement pump male penis elargement prosolution penis elargement pills prosolution penile enlargement pills does pennis enlargement work pennis enlargement device vimax penis enlargement information penis enlargement pic

For those of us who could use a little libido pick-me-up, the grocery store might be a good place to start. Like many aspects of our health, our sex drive is affected by what we put into our bodies. A few drinks and a thick steak, followed by a rich chocolate dessert, may sound romantic, but it is actually a prologue to sleep--not sex. Humans have sought ways to enhance or improve their sex lives for millennia--and have never been reluctant to spend money to make themselves better lovers. The ancient Romans were said to prefer such exotic aphrodisiacs as hippo snouts and hyena eyeballs. Traditional Chinese medicine espoused the use of such rare delicacies as rhino horn. Modern lovers are no less extravagant. In 2004, for example, according to Atlanta-based health care information company NDCHealth , Americans spent about $1.4 billion to treat male sexual function disorders alone. Of that amount, Viagra rang up $997 million in sales for Pfizer or 71.2% of the total market. Among the other drugs trying to find their way into American's bedside tables and back pockets are Levitra, which is made by Bayer but marketed in the U.S. by GlaxoSmithKline and Schering-Plough and Cialis, which was jointly developed by Eli Lilly and ICOS There is a difference, of course, between helping sexual dysfunction and arousing our passions. The problem is that, these days, there are more solutions for the former than the latter. Aphrodisiacs, for the most part, have been proved to be ineffective. Named for Aphrodite, the Greek goddess of sex and beauty, these include an array of herbs, foods and other "agents" that are said to awaken and heighten sexual desire. But the 5,000-year tradition of using them is based more on folklore than real science. "There is no data and no scientific evidence," says Leonore Tiefer, clinical associate professor of psychiatry at the New York University School of Medicine. "Product pushers are very eager to capitalize on myths," she says. Most libido-enhancing products offer short term benefit at best, according to Dr. John Mulhall, Director of the Sexual Medicine Program at New York Presbyterian and associate professor of urology at the Weill Medical College of Cornell University. Mulhall, who also sits on the Nutraceuticals Committee of the Sexual Medicine Society of North America, says: "Every year we review the literature on these compounds--these nutraceuticals like nitric oxide and ginseng--and there are none that have really been shown to be more than a placebo." When it comes to sexual function, the placebo effect is probably 30% in men and around 50% in women, he says. That means there are a lot of people out there who believe a pill they are taking or a food they are eating is doing a lot of good for them sexually. In reality, their mind is doing all the work. So, besides renting The Story of O and opening a bottle of red wine, what can people do to kick start their sex life? One thing they can do is change their diet. Soy, for example, binds estrogen receptors, which helps the vaginal area remain lubricated, and combats symptoms of menopause--particularly hot flashes. Studies have shown that soy is also beneficial to the prostate, a crucial male sex organ. Chili peppers and ginger are believed to improve circulation and stimulate nerve endings, which could, in turn, improve sexual pleasure. Foods that promote weight loss also hold libido-boosting potential. "There has been very solid research showing that obesity is a risk factor for erectile dysfunction and low testosterone," says Dr. Ridwan Shabsigh, director of the New York Center for Human Sexuality and associate professor of urology at Columbia University's medical school. "Reducing weight," he says, "results in an increase of testosterone, and thus an increase in sexual function." "From an erection stand point, anything that's good for your heart is good for your penis," says Dr. Mulhall. Too much saturated fat can, over time, clog arteries and, in doing so, prevent an adequate flow of blood from reaching the genital region. This not only interferes with the ability to perform, but also with sexual pleasure. Too little fat, on the other hand, is also bad. "You need fat to produce your hormones," says Beverly Whipple, professor emeritus at Rutgers University and president of the World Association for Sexology. "Cholesterol is metabolized in the liver, and you get your testosterone and estrogen, which you need for your sex drive," she says. Olive oil, salmon and nuts are optimal sources of the "good" kinds of fats--monounsaturated and polyunsaturated. According to Dr. Judith Reichman, author of I'm Not in the Mood: What Every Woman Should Known about Improving Her Libido, medical and hormonal problems are major contributors to sexual dysfunction and a low libido--but so are too much stress, relationship difficulties and psychological issues. Antidepressants, such as Prozac by GlaxoSmithKline and Paxil by Eli Lilly, can negatively impact sex drive as well. Visit my site http://www.careerpath.cc